With all that in mind, here are just some of the sleeping pills that can be harmful to your health…
1. Zolpidem (like Ambien, Intermezzo, Edluar, or Zolpimist)
In the 2015 car accident study, Zolpidem use was found to be linked to the highest risk of car accidents compared to the other medications studied (3). It’s also linked to other dangerous side effects, like doing activities while you’re asleep that you have no memory of, hallucinations, and symptoms of depression (10).
2. Trazodone (like Desyrel or Oleptro)
Trazodone is primarily an antidepressant, but many doctors prescribe it as a sleep aid as well. Like Zolpidem, Trazodone is associated with a higher risk of car accidents, even after the timeframe that the medication is supposed to have worn off (3). Other harmful side effects include depression, suicidal thoughts, dizziness, low blood pressure, and serotonin syndrome, an interaction that creates dangerous levels of serotonin in the body.
3. Temazepam (like Restoril)
Temazepam is associated with mental health risks, including an increased risk of suicidal thoughts, especially in young people, and abnormal behaviors that don’t fit with your typical personality. There’s also a high risk of addiction and unhealthy withdrawal reactions, and of course, Temazepam was also one of the medications linked in the study to car accident risk (3).
4. Triazolam (like Halcion)
Triazolam is a benzodiazepine, a type of drug that works by increasing the gamma-aminobutyric acid (GABA) in your brain to create a calming effect. Benzodiazepines take effect very quickly, which can be helpful in the short term, but they’re not recommended for regular use. Adults over 65 are at especially high risk of benzodiazepine side effects, like memory problems and falls. In fact, the College of Psychiatric and Neurologic Pharmacists recommends that people over 55 avoid them altogether (11).
5. Eszopiclone (like Lunesta)
Eszopiclone comes with a risk of dependence and withdrawal symptoms. It’s also been associated with feelings of extreme sleepiness during the day, negating the reason you would want to take them in the first place! Like many other sleep aids, this medication comes with the chilling risk of doing an activity while you’re asleep that you don’t remember, as well as uncharacteristic behaviors.
6. Zaleplon (like Sonata)
Zaleplon is part of a class of medications called hypnotics, which means it slows the activity in your brain to encourage sleep. Zaleplon has been linked to sleep-driving, which, terrifyingly enough, is exactly what it sounds like: Driving your car while you’re asleep (12). When you wake up, you may have no memory of doing this. Needless to say, this behavior can be very dangerous or life-threatening.
7. Ramelteon (like Rozerem)
Ramelteon works by mimicking melatonin (we recommend opting for actual melatonin instead, but more on that in a bit). Ramelteon poses a risk for anyone with pre-existing liver disease, and many people experience daytime exhaustion and dizziness while taking it (13). Other side effects include mood changes, suicidal thoughts, and disruption of your menstrual cycle if you are pre-menopause.
8. Suvorexant (like Belsomra)
Suvorexant is a dual orexin receptor antagonist (DORA), a relatively new class of sleep aid. DORAs work by blocking signals in the brain that make you feel awake. They are believed to be less addictive than other prescription sleep aids, but they still come with drawbacks (14). DORAs are associated with the risk of depression, suicidal thoughts, hallucination, sleepwalking, and sleep paralysis.
9. Antihistamines (like Benadryl or Zyrtec)
Antihistamine sleep aids are deceptive. At first, they might seem safer, because they’re over-the-counter medications. But the reality is that they’re recommended for long-term sleep use, and aren’t very effective (15).
The first time you try them, they might work quite well. But soon enough, you’ll notice less and less of their effects (16). Antihistamines also have a knack for lingering in your body longer than you need them, creating a groggy effect the next day (17).
When used for sleep long-term, antihistamines inhibit an important neurotransmitter, potentially putting you at higher risk for dementia and Alzheimer’s disease (18). The longer you take them, the more that risk may increase over time.